Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders

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United States of America Patent

PATENT NO 5405919
SERIAL NO

07935565

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Abstract

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A polymeric composition capable of releasing nitric oxide including a polymer and a nitric oxide-releasing N.sub.2 O.sub.2.sup.- functional group bound to the polymer; pharmaceutical compositions including the polymeric composition; and methods for treating biological disorders in which dosage with nitric oxide is beneficial. The compositions can be used as and/or incorporated into implants, injectables, condoms, prosthesis coatings, patches, and the like for use in a wide variety of medical applications.

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Patent Owner(s)

Patent OwnerAddress
UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICESC/O NATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY TRANSFER BOX OTT BETHESDA MD 20892

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hrabie, Joseph A Frederick, MD 27 1481
Keefer, Larry K Bethesda, MD 54 3091

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