Sustained release composition for oral administration of active ingredient
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United States of America Patent
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-
Apr 18, 1995
Issued Date -
N/A
app pub date -
Jan 29, 1992
filing date -
Nov 27, 1991
priority date (Note) -
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status (Latency Note)
Importance
Abstract
A sustained release tablet adapted to provide an initial immediate release of an active agent, a period of no release of the active agent, followed by a substantially constant, rate of release of the active agent. The tablet includes (a) a compressed tablet core containing an active agent, an insoluble binder and an insoluble; (b) a barrier coating formed over the tablet core, the barrier coating including a mixture of soluble and insoluble polymers and a plasticizer; (c) an active coating deposited over the barrier coating, the active coating including an active agent, a soluble polymer and a plasticizer; and (d) a film coating formed over the active coating, the film coating containing a soluble polymer and plasticizer.
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