Process and apparatus for direct determination of low density lipoprotein
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United States of America Patent
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May 2, 1995
Issued Date -
N/A
app pub date -
Dec 11, 1992
filing date -
Dec 13, 1991
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Abstract
Low density lipoproteins are directly determined in fluid samples by selectively precipitating low density lipoproteins from the sample by forming clusters, selectively consuming the high density and very low density lipoproteins, and resolubilizing the low density lipoproteins for direct determination thereof. The clusters are formed by treating the fluid sample with a mixture of a polyanionic compound, a divalent metal, and a nucleating agent. The clusters are redissolved and assayed for low density lipoproteins.
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