Cocaine receptor binding ligands

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United States of America Patent

PATENT NO 5413779
SERIAL NO

07972472

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Abstract

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3.beta.-[4-iodophenyl]-tropan-2.beta.-carboxylic acid methyl ester tartrate is a high affinity binding ligand for cocaine receptors in mammalian brains. It and its congeners may be employed for imaging and other brain scanning techniques that allow the determination of the presence of cocaine receptors, such as dopamine and serotonin transporters and the like.

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Patent Owner(s)

Patent OwnerAddress
UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES9000 ROCKVILLE PIKE BETHESDA MD 20892 MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abraham, Philip Cary, NC 40 487
Boja, John W Baltimore, MD 12 229
Carroll, Frank I Durham, NC 29 484
Kuhar, Michael J Baltimore, MD 14 268
Lewin, Anita H Chapel Hill, NC 16 267

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