Method and composition having enhanced alpha-hydroxy acid skin permeation and retention
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United States of America Patent
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May 30, 1995
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N/A
app pub date -
Mar 22, 1994
filing date -
Mar 22, 1994
priority date (Note) -
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Abstract
Methods of enhancing skin permeation and skin retention of .alpha.-hydroxy acids for the treatment of dermatological disorders by applying a composition containing an amphoteric salt of an .alpha.-hydroxy acid, such as lactic, glycolic, citric, tartaric or malic acid and an amino acid, dipepdide, polypeptide or proteins, in a dermatologically acceptable carrier which contains 0.5 to 8% glycerol monocaprylate, 0 to 80% petrolatum and 0 to 30% isopropyl myristrate, the pH of the composition being from 3 to 9, and compositions for practicing such methods.
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