US Patent No: 5,423,807

Number of patents in Portfolio can not be more than 2000

Cryogenic mapping and ablation catheter

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Abstract

The invention provides a catheter for ice mapping and ablation and a method of ablation using the catheter. The catheter includes at least two conduits for circulating a refrigerating fluid adjacent an ablation device located at the end of a catheter. The refrigerated ablation device is used to chill a localized region of myocardial tissue, thereby permitting the resulting change in electrical activity to be determined. In response to the test results, the ablation device may be used to make a lesion in the myocardial tissue to correct a cardiac arrhythmia. In one embodiment, the ablation device is an electrode which uses radio frequency energy to ablate the myocardial tissue. Alternatively, the ablation device is an electrode adapted for direct current ablation. In another embodiment, the electrode is replaced with an optical fiber in communication with a laser which uses the laser's light energy to ablate tissue. Yet another embodiment is a cryogenic catheter having combined or separate mapping and ablation devices. In another embodiment, a cryogenic catheter is provided having an inner conduit with a stepped down diameter. The embodiments may include provisions for steering the catheter and for stabilizing the ablation device at the proposed lesion site.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MEDTRONIC CRYOCATH LPTORONTO ONTARIO107

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Milder, Fredric L Brookline, MA 37 2581

Cited Art

Patent Info (Count) # Cites Year
 
MEDTRONIC CRYOCATH LP (4)
5,147,355 Cryoablation catheter and method of performing cryoablation 412 1988
5,139,496 Ultrasonic freeze ablation catheters and probes 171 1990
5,281,213 Catheter for ice mapping and ablation 470 1992
5,281,215 Cryogenic catheter 380 1992
 
ERBE ELEKTROMEDIZIN KG (2)
4,202,336 Cauterizing probes for cryosurgery 52 1978
4,278,090 Cryosurgical device 91 1979
 
ANAND; RAJ K. (1)
4,860,744 Thermoelectrically controlled heat medical catheter 383 1987
 
BRACK GILLIUM HATTLER (1)
4,406,656 Venous catheter having collapsible multi-lumens 275 1981
 
COOPERSURGICAL, INC. (1)
5,275,595 Cryosurgical instrument 170 1992
 
ENDOCARE, INC. (1)
5,254,116 Cryosurgical instrument with vent holes and method using same 135 1991
 
FRIGITRONICS, INC., 770 RIVER ROAD, SHELTON, CONNECTICUT 06484, A DE. CORP. (1)
5,108,390 Flexible cryoprobe 251 1988
 
SPEMBLY MEDICAL LIMITED (1)
4,207,897 Cryosurgical probe 189 1977
 
VALLEYLAB INC. (1)
4,275,734 Cryosurgical apparatus and method 167 1977
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
4,519,389 Thermoelectric cryoprobe 85 1982

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
INNERCOOL THERAPIES, INC., A DELAWARE CORPORATION (84)
6,051,019 Selective organ hypothermia method and apparatus 141 1998
6,042,559 Insulated catheter for selective organ perfusion 161 1998
5,957,963 Selective organ hypothermia method and apparatus 190 1998
6,231,595 Circulating fluid hypothermia method and apparatus 107 1998
6,096,068 Selective organ cooling catheter and method of using the same 158 1998
6,254,626 Articulation device for selective organ cooling apparatus 100 1998
6,251,129 Method for low temperature thrombolysis and low temperature thrombolytic agent with selective organ temperature control 103 1998
6,238,428 Selective organ cooling apparatus and method employing turbulence-inducing element with curved terminations 93 1999
6,312,452 Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device 99 1999
6,224,624 Selective organ cooling apparatus and method 113 1999
6,235,048 Selective organ hypothermia method and apparatus 102 1999
6,149,677 Circulating fluid hypothermia method 147 1999
6,843,800 Patient temperature regulation method and apparatus 1 1999
6,325,818 Inflatable cooling apparatus for selective organ hypothermia 68 1999
6,379,378 Lumen design for catheter 68 2000
6,491,039 Medical procedure 15 2000
6,471,717 Selective organ cooling apparatus and method 13 2000
6,464,716 Selective organ cooling apparatus and method 27 2000
6,582,455 Method and device for applications of selective organ cooling 16 2000
6,482,226 Selective organ hypothermia method and apparatus 14 2000
6,478,811 Method for low temperature thrombolysis and low temperature thrombolytic agent with selective organ temperature control 17 2000
6,468,296 Method for low temperature thrombolysis and low temperature thrombolytic agent with selective organ temperature control 24 2000
6,719,723 Multipurpose catheter assembly 9 2000
6,576,002 Isolated selective organ cooling method and apparatus 16 2001
6,478,812 Method and device for applications of selective organ cooling 19 2001
6,475,231 Method and device for applications of selective organ cooling 18 2001
6,540,771 Inflatable catheter for selective organ heating and cooling and method of using the same 27 2001
6,533,804 Inflatable catheter for selective organ heating and cooling and method of using the same 21 2001
6,818,011 Circulating fluid hypothermia method and apparatus 4 2001
6,602,276 Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 40 2001
6,551,349 Selective organ cooling apparatus 22 2001
6,648,906 Method and apparatus for regulating patient temperature by irrigating the bladder with a fluid 23 2001
6,692,488 Apparatus for cell necrosis 13 2001
6,558,412 Selective organ hypothermia method and apparatus 13 2001
6,676,688 Method of making selective organ cooling catheter 14 2001
6,599,312 Isolated selective organ cooling apparatus 20 2001
6,726,708 Therapeutic heating and cooling via temperature management of a colon-inserted balloon 21 2001
6,905,509 Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device 5 2001
6,685,732 METHOD AND DEVICE FOR PERFORMING COOLING- OR CRYO-THERAPIES FOR, E.G., ANGIOPLASTY WITH REDUCED RESTENOSIS OR PULMONARY VEIN CELL NECROSIS TO INHIBIT ATRIAL FIBRILLATION EMPLOYING MICROPOROUS BALLOON 27 2001
6,719,779 Circulation set for temperature-controlled catheter and method of using the same 33 2001
6,585,752 Fever regulation method and apparatus 16 2001
6,576,001 Lumen design for catheter 24 2001
6,786,218 Medical procedure 4 2001
7,291,144 Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 3 2002
6,660,028 Method for determining the effective thermal mass of a body or organ using a cooling catheter 17 2002
6,905,494 Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection 16 2002
7,001,378 Method and device for performing cooling or cryo-therapies, for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection 14 2002
6,695,873 Inflatable catheter for selective organ heating and cooling and method of using the same 16 2002
6,676,689 Inflatable catheter for selective organ heating and cooling and method of using the same 16 2002
6,648,908 Inflatable catheter for selective organ heating and cooling and method of using the same 37 2002
6,755,850 Selective organ hypothermia method and apparatus 10 2002
6,991,645 Patient temperature regulation method and apparatus 0 2002
6,702,842 Selective organ cooling apparatus and method 17 2002
6,979,345 Multipurpose catheter assembly 2 2002
6,869,440 Method and apparatus for patient temperature control employing administration of anti-shivering agents 5 2002
6,830,581 Method and device for patient temperature control employing optimized rewarming 3 2002
7,101,386 Patient temperature regulation method and apparatus 17 2002
6,595,967 Collapsible guidewire lumen 12 2002
6,887,262 Selective organ cooling apparatus and method 3 2002
6,740,109 Isolated selective organ cooling method 13 2002
7,063,718 Selective organ hypothermia method and apparatus 5 2003
7,094,253 Fever regulation method and apparatus 0 2003
7,004,960 Circulation set for temperature-controlled catheter and method of using the same 3 2003
7,651,518 Inflatable catheter for selective organ heating and cooling and method of using the same 0 2003
6,918,924 Method and apparatus for regulating patient temperature by irrigating the bladder with a fluid 6 2003
7,052,508 Inflatable heat transfer apparatus 0 2003
7,211,105 Method for determining the effective thermal mass of a body or organ using a cooling catheter 0 2003
7,018,399 Method of making selective organ cooling catheter 4 2003
7,449,018 Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing microporous balloon 0 2004
7,066,948 Selective organ cooling apparatus and method 0 2004
7,491,223 Therapeutic heating and cooling via temperature management of a colon-inserted balloon 2 2004
7,189,254 Method and device for patient temperature control employing optimized rewarming 4 2004
7,371,254 Medical procedure 3 2004
7,351,254 Method and device for patient temperature control employing optimized rewarming 5 2004
7,422,600 Method and apparatus for patient temperature control employing administration of anti-shivering agents 1 2005
7,288,089 Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection 6 2005
7,998,182 Selective organ cooling apparatus 0 2006
7,311,725 Patient temperature regulation method and apparatus 3 2006
7,766,949 Fever regulation method and apparatus 0 2006
8,157,794 Method and device for performing cooling-or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 0 2007
8,043,351 Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection 0 2007
8,043,283 Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation 0 2007
8,163,000 Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device 0 2007
7,951,183 Medical procedure 0 2008
 
MEDTRONIC, INC. (51)
5,913,854 Fluid cooled ablation catheter and method for making 101 1997
7,967,816 Fluid-assisted electrosurgical instrument with shapeable electrode 1 2002
7,507,235 Method and system for organ positioning and stabilization 6 2002
7,294,143 Device and method for ablation of cardiac tissue 19 2003
7,118,566 Device and method for needle-less interstitial injection of fluid for ablation of cardiac tissue 18 2003
7,497,857 Endocardial dispersive electrode for use with a monopolar RF ablation pen 1 2003
7,615,015 Focused ultrasound ablation devices having selectively actuatable emitting elements and methods of using the same 5 2003
7,083,620 Electrosurgical hemostat 102 2003
7,367,972 Ablation system 52 2003
7,347,858 Method and system for treatment of atrial tachyarrhythmias 1 2003
7,169,144 Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue 78 2003
7,094,235 Method and apparatus for tissue ablation 13 2004
8,162,933 Vibration sensitive ablation device and method 0 2004
8,333,764 Device and method for determining tissue thickness and creating cardiac ablation lesions 0 2004
7,247,155 Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue 90 2004
7,470,272 Device and method for ablating tissue 30 2004
7,250,048 Ablation system and method of use 51 2004
7,628,780 Devices and methods for interstitial injection of biologic agents into tissue 1 2004
7,364,578 System and method of performing an electrosurgical procedure 41 2004
7,963,963 Electrosurgical hemostat 6 2005
7,435,250 Method and apparatus for tissue ablation 4 2005
7,706,894 Heart wall ablation/mapping catheter and method 3 2005
7,706,882 Methods of using high intensity focused ultrasound to form an ablated tissue area 0 2005
7,758,576 Clamping ablation tool and method 1 2005
7,758,580 Compound bipolar ablation device and method 0 2005
7,678,108 Loop ablation apparatus and method 0 2005
7,566,334 Ablation device with jaws 24 2005
7,740,623 Devices and methods for interstitial injection of biologic agents into tissue 2 2005
7,309,325 Helical needle apparatus for creating a virtual electrode used for the ablation of tissue 26 2005
7,818,039 Suction stabilized epicardial ablation devices 0 2005
7,156,845 Method and apparatus for creating a bi-polar virtual electrode used for the ablation of tissue 35 2005
7,166,105 Pen-type electrosurgical instrument 33 2005
7,678,111 Device and method for ablating tissue 9 2005
8,221,402 Method for guiding a medical device 0 2005
7,824,399 Ablation system and method of use 0 2006
7,250,051 Method and apparatus for tissue ablation 9 2006
7,975,703 Device and method for needle-less interstitial injection of fluid for ablation of cardiac tissue 1 2006
7,744,562 Devices and methods for interstitial injection of biologic agents into tissue 0 2006
8,414,573 Device and method for ablation of cardiac tissue 0 2006
7,422,588 Pen-type electrosurgical instrument 2 2006
7,959,626 Transmural ablation systems and methods 19 2007
8,262,649 Method and apparatus for tissue ablation 0 2007
8,221,415 Method and apparatus for tissue ablation 0 2007
7,699,805 Helical coil apparatus for ablation of tissue 4 2007
7,794,460 Method of ablating tissue 0 2008
7,871,409 Endocardial dispersive electrode for use with a monopolar RF ablation pen 0 2009
7,875,028 Ablation device with jaws 0 2009
8,409,219 Method and system for placement of electrical lead inside heart 0 2009
8,273,072 Devices and methods for interstitial injection of biologic agents into tissue 0 2009
8,172,837 Clamping ablation tool and method 0 2010
8,162,941 Ablation device with jaws 0 2010
 
MEDTRONIC CRYOCATH LP (31)
5,899,898 Cryosurgical linear ablation 190 1997
5,899,899 Cryosurgical linear ablation structure 262 1997
6,235,019 Cryosurgical catheter 50 1998
6,270,476 Catheter 92 1999
6,280,439 Adjustable position injection tubing 17 1999
6,270,493 Cryoablation structure 61 1999
7,097,641 Catheter with cryogenic and heating ablation 8 1999
6,468,268 Cryogenic catheter system 34 2000
6,440,126 Cryoblation catheter handle 23 2000
6,629,972 Cryosurgical catheter 12 2001
6,540,740 Cryosurgical catheter 50 2001
6,736,809 Method and device for treatment of aneurysms 1 2001
6,589,234 Cryogenic medical device with high pressure resistance tip 25 2001
6,579,287 Cryosurgical ablation device having sequential injection and method therefor 14 2001
6,669,689 Cryosurgical catheter 24 2002
6,602,247 Apparatus and method for performing a treatment on a selected tissue region 16 2002
6,730,077 Catheter system 2 2002
6,887,234 Cryogenic catheter system 2 2002
7,727,228 Method and apparatus for inflating and deflating balloon catheters 1 2004
8,206,345 Fluid control system for a medical device 0 2005
7,591,814 Extended treatment zone catheter 0 2005
7,912,554 Method for treatment of aneurysms 0 2005
7,465,300 Catheter with cryogenic and electrical heating ablation 2 2005
7,753,905 Cryosurgical catheter 0 2005
7,896,870 Catheter with cryogenic and electrical heating ablation 0 2007
8,382,747 Method and apparatus for inflating and deflating balloon catheters 0 2007
7,951,140 Catheter with cryogenic and electrical heating ablation 0 2008
8,043,284 Cryosurgical catheter 0 2010
7,914,526 Cryosurgical catheter 0 2010
8,083,732 Catheter with cryogenic and electrical heating ablation 0 2011
8,287,526 Method of simultaneously freezing and heating tissue for ablation 0 2011
 
BOSTON SCIENTIFIC SCIMED, INC. (30)
5,868,735 Cryoplasty device and method 170 1997
6,290,696 Cryoplasty device and method 71 1999
7,220,257 Cryotreatment device and method 5 2000
6,666,858 Cryo balloon for atrial ablation 36 2001
6,648,878 Cryoplasty device and method 26 2001
6,709,431 Cryo-temperature monitoring 10 2001
6,989,009 Cryo balloon 19 2002
7,938,828 Cooled ablation catheter 0 2003
7,022,120 Cryoplasty device and method 5 2003
7,101,368 Cryo balloon for atrial ablation 1 2003
8,235,976 Cryo-temperature monitoring 0 2004
7,582,083 Probe based low temperature lesion formation apparatus, systems and methods 0 2004
7,291,142 Low temperature lesion formation apparatus, systems and methods 0 2004
7,288,088 Clamp based low temperature lesion formation apparatus, systems and methods 4 2004
7,674,256 Treating internal body tissue 1 2005
7,189,227 Cryo balloon 1 2005
7,306,589 Therapeutic apparatus having insulated region at the insertion area 2 2005
7,306,590 Therapeutic apparatus having insulated region at the insertion area 1 2005
7,850,681 Cryoplasty device and method 5 2006
7,485,109 Targeted cooling of tissue within a body 0 2006
7,291,143 Clamp based low temperature lesion formation apparatus, systems and methods 5 2006
7,160,290 Low temperature lesion formation apparatus, systems and methods 0 2006
8,012,147 Cryotreatment device and method 1 2007
8,142,424 Probe based low temperature lesion formation apparatus, systems and methods 0 2007
7,972,327 Low temperature lesion formation apparatus, systems and methods 0 2007
7,861,725 Method for monitoring formation of a lesion in a tissue structure using a cryogenic system 0 2007
8,123,741 Treating internal body tissue 0 2009
8,048,066 Cryotreatment device and method of forming conduction blocks 0 2009
8,088,125 Cryoplasty device and method 0 2010
8,409,266 Cryotreatment device and method 0 2011
 
ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (27)
6,311,692 Apparatus and method for diagnosis and therapy of electrophysiological disease 229 1999
6,484,727 Apparatus and method for diagnosis and therapy of electrophysiological disease 138 1999
6,474,340 Apparatus and method for diagnosis and therapy of electrophysiological disease 159 1999
6,314,962 Method of ablating tissue around the pulmonary veins 253 1999
6,314,963 Method of ablating tissue from an epicardial location 248 1999
6,805,128 Apparatus and method for ablating tissue 79 2000
6,805,129 Apparatus and method for ablating tissue 74 2000
6,645,202 Apparatus and method for ablating tissue 143 2000
6,719,755 Methods and devices for ablation 65 2001
6,858,026 Methods and devices for ablation 51 2001
6,701,931 Methods and devices for ablation 79 2001
6,689,128 Methods and devices for ablation 84 2001
6,840,936 Methods and devices for ablation 42 2002
7,387,126 Surgical system and procedure for treatment of medically refractory atrial fibrillation 12 2002
6,949,095 Apparatus and method for diagnosis and therapy of electrophysiological disease 36 2002
7,338,486 Methods and devices for ablation 5 2002
6,971,394 Methods and devices for ablation 51 2002
7,674,257 Apparatus and method for ablating tissue 5 2004
8,114,069 Methods and devices for ablation 0 2005
7,824,402 Methods and devices for ablation 1 2006
7,824,403 Methods and devices for ablation 2 2006
7,857,811 Methods and devices for ablation 0 2006
8,057,465 Methods and devices for ablation 1 2007
8,002,771 Surgical system and procedure for treatment of medically refractory atrial fibrillation 0 2007
8,211,096 Apparatus and method for ablating tissue 1 2007
8,308,719 Apparatus and method for ablating tissue 0 2007
8,177,780 Surgical system and procedure for treatment of medically refractory atrial fibrillation 0 2009
 
THERMAGE, INC. (25)
6,241,753 Method for scar collagen formation and contraction 149 1996
5,871,524 Apparatus for controlled contraction of collagen tissue 104 1997
6,470,216 Method for smoothing contour irregularities of skin surface 67 1997
6,461,378 Apparatus for smoothing contour irregularities of skin surface 46 1997
6,430,446 Apparatus for tissue remodeling 58 1997
5,919,219 Method for controlled contraction of collagen tissue using RF energy 132 1997
6,425,912 Method and apparatus for modifying skin surface and soft tissue structure 103 1997
5,948,011 Method for controlled contraction of collagen tissue via non-continuous energy delivery 147 1997
6,377,854 Method for controlled contraction of collagen in fibrous septae in subcutaneous fat layers 51 1997
6,438,424 Apparatus for tissue remodeling 52 1998
6,381,497 Method for smoothing contour irregularity of skin surface by controlled contraction of collagen tissue 55 1998
6,381,498 Method and apparatus for controlled contraction of collagen tissue 71 1998
6,377,855 Method and apparatus for controlled contraction of collagen tissue 70 1998
6,350,276 Tissue remodeling apparatus containing cooling fluid 145 1999
6,453,202 Method and apparatus for controlled contraction of collagen tissue 62 1999
6,749,624 Fluid delivery apparatus 109 2001
7,141,049 Handpiece for treatment of tissue 25 2002
7,022,121 Handpiece for treatment of tissue 33 2002
7,452,358 RF electrode assembly for handpiece 26 2003
7,267,675 RF device with thermo-electric cooler 28 2003
7,229,436 Method and kit for treatment of tissue 14 2003
7,115,123 Handpiece with electrode and non-volatile memory 129 2003
7,006,874 Treatment apparatus with electromagnetic energy delivery device and non-volatile memory 30 2003
7,189,230 Method for treating skin and underlying tissue 26 2003
7,481,809 Handpiece with RF electrode and non-volatile memory 12 2005
 
ZOLL CIRCULATION, INC. (21)
6,458,150 Method and apparatus for patient temperature control 30 1999
6,450,990 Catheter with multiple heating/cooling fibers employing fiber spreading features 24 1999
6,368,304 Central venous catheter with heat exchange membrane 68 1999
6,165,207 Method of selectively shaping hollow fibers of heat exchange catheter 87 1999
6,287,326 Catheter with coiled multi-lumen heat transfer extension 114 1999
6,419,643 Central venous catheter with heat exchange properties 52 1999
6,447,474 Automatic fever abatement system 27 1999
6,299,599 Dual balloon central venous line catheter temperature control system 111 1999
6,409,747 Indwelling heat exchange catheter and method of using same 46 2000
6,582,398 Method of managing patient temperature with a heat exchange catheter 16 2000
6,516,224 Method for treating cardiac arrest 14 2001
6,393,320 Method for treating cardiac arrest 63 2001
6,620,131 Dual balloon central venous line catheter temperature control system 13 2001
8,128,595 Method for a central venous line catheter having a temperature control system 0 2001
6,652,565 Central venous catheter with heat exchange properties 17 2001
6,716,236 Intravascular catheter with heat exchange element having inner inflation element and methods of use 13 2001
6,572,640 Method and apparatus for cardiopulmonary bypass patient temperature control 17 2001
6,589,271 Indwelling heat exchange catheter 27 2001
6,755,851 Indwelling heat exchange catheter and method of using same 15 2002
7,278,984 System and method for controlling rate of heat exchange with patient 3 2002
7,641,632 System and method for controlling rate of heat exchange with patient 0 2007
 
ANGIODYNAMICS, INC. (20)
5,683,384 Multiple antenna ablation apparatus 188 1995
5,863,290 Multiple antenna ablation apparatus and method 114 1995
5,782,827 Multiple antenna ablation apparatus and method with multiple sensor feedback 68 1995
5,735,847 Multiple antenna ablation apparatus and method with cooling element 132 1995
5,672,173 Multiple antenna ablation apparatus and method 58 1995
6,689,127 Multiple antenna ablation apparatus and method with multiple sensor feedback 12 1995
5,672,174 Multiple antenna ablation apparatus and method 203 1996
5,728,143 Multiple antenna ablation apparatus and method 99 1996
5,810,804 Multiple antenna ablation apparatus and method with cooling element 167 1996
6,071,280 Multiple electrode ablation apparatus 99 1997
5,928,229 Tumor ablation apparatus 49 1997
6,958,062 Multiple antenna ablation apparatus and method 6 1997
5,951,547 Multiple antenna ablation apparatus and method 84 1997
5,925,042 Multiple antenna ablation apparatus and method 53 1997
5,913,855 Multiple antenna ablation apparatus and method 62 1997
6,059,780 Multiple antenna ablation apparatus and method with cooling element 63 1997
6,090,105 Multiple electrode ablation apparatus and method 74 1997
6,132,425 Cell necrosis apparatus 34 1998
6,080,150 Cell necrosis apparatus 59 1998
5,980,517 Cell necrosis apparatus 83 1998
 
ATRICURE, INC. (20)
6,546,935 Method for transmural ablation 92 2000
6,517,536 Transmural ablation device and method 144 2001
7,604,634 Transmural ablation device 0 2001
7,113,831 Transmural ablation device 15 2001
7,001,415 Transmural ablation device 19 2001
6,974,454 Transmural ablation device with thermocouple for measuring tissue temperature 35 2001
6,923,806 Transmural ablation device with spring loaded jaws 28 2001
6,899,710 Combination ablation and visualization apparatus for ablating cardiac tissue 28 2001
6,889,694 Transmural ablation device 34 2001
6,905,498 Transmural ablation device with EKG sensor and pacing electrode 31 2002
7,291,161 Articulated clamping member 8 2002
7,241,292 Cardiac ablation device with movable hinge 8 2002
6,896,673 Method for transmural ablation 32 2002
7,288,092 Method and apparatus for ablating cardiac tissue with guide facility 3 2004
7,393,353 Transmural ablation device with temperature sensor 1 2004
7,487,780 Sub-xyphoid method for ablating cardiac tissue 65 2004
7,468,061 Transmural ablation device with integral EKG sensor 0 2004
6,984,233 Transmural ablation device with parallel electrodes 12 2004
7,530,980 Bipolar transmural ablation method and apparatus 1 2005
7,543,589 Method for ablating cardiac tissue 0 2007
 
MAQUET CARDIOVASCULAR LLC (11)
7,033,352 Flexible ablation instrument 15 2000
7,099,717 Catheter having improved steering 4 2002
7,052,491 Vacuum-assisted securing apparatus for a microwave ablation instrument 11 2002
7,115,126 Directional microwave ablation instrument with off-set energy delivery portion 16 2002
7,192,427 Apparatus and method for assessing transmurality of a tissue ablation 34 2003
6,976,986 Electrode arrangement for use in a medical instrument 37 2004
7,303,560 Method of positioning a medical instrument 6 2004
7,346,399 Monopole tip for ablation catheter 3 2004
7,156,841 Electrode arrangement for use in a medical instrument 1 2005
7,387,627 Vacuum-assisted securing apparatus for a microwave ablation instrument 12 2005
7,301,131 Microwave ablation instrument with flexible antenna assembly and method 15 2006
 
COOPERSURGICAL, INC. (10)
5,758,505 Precooling system for joule-thomson probe 51 1996
6,530,234 Precooling system for Joule-Thomson probe 11 1998
6,241,722 Cryogenic device, system and method of using same 118 1998
6,182,666 Cryosurgical probe and method for uterine ablation 78 1998
6,193,644 Cryosurgical probe with sheath 35 1999
6,270,494 Stretchable cryoprobe sheath 36 1999
6,451,012 Cryosurgical method for endometrial ablation 16 2001
6,475,212 Cryosurgical probe with sheath 21 2001
RE40815 Control system for cryosurgery 0 2007
8,298,221 Disposable sheath with replaceable console probes for cryosurgery 0 2007
 
CRYOCOR, INC. (9)
6,955,673 Heat transfer segment for a cryoablation catheter 2 2002
7,004,936 Refrigeration source for a cryoablation catheter 1 2002
6,981,382 Distal end for cryoablation catheters 3 2003
7,070,594 System and method for assessing ice ball formation during a cryoablation procedure 2 2004
7,195,625 Catheter system for performing a single step cryoablation 2 2004
7,156,840 Pressure monitor for cryoablation catheter 3 2004
7,357,797 System and method for varying return pressure to control tip temperature of a cryoablation catheter 0 2004
7,163,535 System for detecting leaks and occlusions in a cryoablation catheter 1 2004
RE40868 Refrigeration source for a cryoblation catheter 0 2007
 
ENDOSENSE SA (6)
8,182,433 Medical apparatus system having optical fiber load sensing capability 0 2005
8,075,498 Medical apparatus system having optical fiber load sensing capability 4 2006
8,048,063 Catheter having tri-axial force sensor 4 2006
8,157,789 Touch sensing catheter 1 2007
8,298,227 Temperature compensated strain sensing catheter 0 2008
8,435,232 Catheter having tri-axial force sensor 0 2011
 
ICECURE MEDICAL LTD. (6)
8,083,733 Cryosurgical instrument with enhanced heat exchange 0 2009
7,967,814 Cryoprobe with vibrating mechanism 0 2010
8,162,812 Combined cryotherapy and brachytherapy device and method 0 2010
7,967,815 Cryosurgical instrument with enhanced heat transfer 0 2010
7,938,822 Heating and cooling of cryosurgical instrument using a single cryogen 0 2010
8,080,005 Closed loop cryosurgical pressure and flow regulated system 0 2010
 
BIOSENSE WEBSTER, INC. (5)
6,602,242 Irrigated tip catheter 59 2000
6,497,703 Cryoablation catheter for long lesion ablations 6 2000
6,551,274 Cryoablation catheter with an expandable cooling chamber 24 2001
6,585,728 Cryoablation catheter with an improved gas expansion chamber 9 2001
6,547,785 Cryoablation catheter for long lesion ablations 11 2001
 
DEL MAR MEDICAL TECHNOLOGIES (4)
6,261,312 Inflatable catheter for selective organ heating and cooling and method of using the same 109 1998
6,251,130 Device for applications of selective organ cooling 111 1998
6,245,095 Method and apparatus for location and temperature specific drug action such as thrombolysis 106 1999
6,491,716 Method and device for applications of selective organ cooling 13 1999
 
HALT MEDICAL INC. (4)
7,678,106 Gynecological ablation procedure and system 4 2005
8,080,009 Radio frequency ablation device for the destruction of tissue masses 0 2005
8,251,991 Anchored RF ablation device for the destruction of tissue masses 0 2007
8,241,276 RF ablation device with jam-preventing electrical coupling member 0 2007
 
RECOR MEDICAL, INC. (4)
7,083,614 Thermal treatment methods and apparatus with focused energy application 25 2002
7,837,676 Cardiac ablation devices 0 2004
7,326,201 Thermal treatment methods and apparatus with focused energy application 16 2005
7,540,846 Energy application with inflatable annular lens 0 2005
 
KIMBERLY-CLARK INC. (3)
8,043,287 Method of treating biological tissue 0 2005
8,201,563 Method for introducing materials into a body 1 2006
8,096,957 Method for removing material from a patient's body 0 2006
 
BACOUSTICS, LLC (2)
7,540,870 Ablative ultrasonic-cryogenic apparatus 10 2007
8,062,289 Ablative ultrasonic-cryogenic apparatus 0 2009
 
GYRUS MEDICAL LIMITED (2)
6,942,662 Surgical Instrument 151 2002
7,211,084 Surgical system 27 2005
 
ORIGIN MEDSYSTEMS, INC. (2)
6,623,514 Method of cooling an organ 5 2001
6,972,028 Method of cooling an organ 5 2003
 
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (2)
5,716,386 Non-invasive aortic impingement and core and cerebral temperature manipulation 213 1996
6,296,654 Non-invasive aortic impingement 62 2000
 
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE (2)
6,151,901 Miniature mixed gas refrigeration system 13 1995
5,787,715 Mixed gas refrigeration method 32 1996
 
THERMOPEUTIX, INC. (2)
7,789,846 System and methods for selective thermal treatment 0 2005
7,704,220 Systems and methods for selective thermal treatment 0 2006
 
ABLATION PRODUCTS, INC. (1)
6,187,346 Intrauterine chemical cauterizing method and composition 11 1997
 
AMERICAN MEDICAL SYSTEMS GYNECOLOGY, INC. (1)
5,956,958 Gas mixture for cryogenic applications 5 1997
 
APPLIED CRYONEUROLOGICS LLC (1)
6,761,715 Method and device for neurocryo analgesia and anesthesia 29 2002
 
ARX, INC. (1)
7,226,446 Surgical microwave ablation assembly 20 2000
 
BIOTRONIK MESS-UND THERAPIEGERAETE GMBH & CO. (1)
7,167,759 Electrode line 0 2002
 
CORDIS WEBSTER, INC. (1)
6,120,476 Irrigated tip catheter 83 1997
 
EDWARDS LIFESCIENCES CORPORATION (1)
7,731,715 Ablative treatment of atrial fibrillation via the coronary sinus 0 2004
 
ENDOCARE, INC. (1)
6,379,348 Combined electrosurgical-cryosurgical instrument 55 2000
 
EPICOR, INC. (1)
6,161,543 Methods of epicardial ablation for creating a lesion around the pulmonary veins 417 1997
 
FEMRX, INC. (1)
6,306,129 Cryosurgical system and method 45 1999
 
HEARTPOINT, INC. (1)
6,237,605 Methods of epicardial ablation 313 1998
 
IHD, INC. (1)
5,865,833 Apparatus for laser treatment 3 1997
 
MEDCOOL, INC. (1)
7,094,234 Interstitial brain cooling probe and sheath apparatus 3 2002
 
NEUROTHERMIA, INC. (1)
6,676,690 Inflatable heat transfer apparatus 14 2001
 
NEW ENGLAND MEDICAL CENTER (1)
7,041,095 Cardiac ablation system and method for treatment of cardiac arrhythmias and transmyocardial revascularization 5 2003
 
NEWMAN, ALLEN (1)
6,450,948 Deflecting tip for surgical cannula 24 1999
 
NIDUS MEDICAL, LLC (1)
7,758,571 Methods and apparatus for cryo-therapy 0 2002
 
NUVUE THERAPEUTICS, INC. (1)
6,551,309 Dual action cryoprobe and methods of using the same 34 2000
 
SECRETARY OF COMMERCE (1)
5,901,783 Cryogenic heat exchanger 26 1997
 
TECMACHINE (1)
6,932,811 Transmural ablation device with integral EKG sensor 23 2001
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (8)
5,693,077 Treatment of vascular and tension headache atypical facial pain allergic rhinitis and cervical muscle hyperactivity 3 1996
5,891,457 Intrauterine chemical necrosing method, composition, and apparatus 39 1997
6,197,351 Intrauterine chemical necrosing method and composition 24 1997
6,508,814 Method and apparatus for rupturing targeted cells 7 1998
6,165,492 Intrauterine chemical necrosing method, composition, and apparatus 11 1999
6,579,110 Connection assembly for conduits 0 2001
7,128,740 Method for interrupting conduction paths within the heart 5 2003
8,439,905 Nucleation enhanced surface modification to support physical vapor deposition to create a vacuum 0 2009