Vaccines containing avirulent phop-type microorganisms
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jun 13, 1995
Issued Date -
N/A
app pub date -
Nov 19, 1992
filing date -
Mar 31, 1989
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The phoP gene and its equivalents are of a type which have 'global regulation of pathogenicity', i.e., they coordinately regulate a number of genes including those that encode bacterial virulence factors. In Salmonella, the phoP gene product also controls the expression of non-specific acid phosphatase from the phoN gene. A central feature of the invention are microorganisms which are avirulent as a result, in whole or in part, of a mutation in phoP, but which retain their immunogenicity. These cells are suitable as components of live vaccines.
First Claim
Family
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully