Method for immunization of mammals against atherosclerosis and pharmaceutical compositions for obtaining said immunization
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United States of America Patent
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Jun 13, 1995
Grant Date -
N/A
app pub date -
Mar 5, 1993
filing date -
Dec 7, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Pharmaceutical compositions and a method for immunization of mammals against atherosclerosis including steps of a) obtaining blood from a mammal; b) isolating low density lipoprotein from the blood; c) fusing the lipoprotein in vitro to obtain heavy microemulsion lipoprotein fusion particles having new antigenic determinants; d) administering the fusion particles obtained in step (c) to a mammal; and e) allowing the immune system to clear fusion lipoprotein particles from the mammal.
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