Screening method for chronic immune dysfunction syndrome
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United States of America Patent
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Jun 20, 1995
Issued Date -
N/A
app pub date -
Nov 4, 1991
filing date -
Jul 5, 1991
priority date (Note) -
Expired
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Abstract
The subject invention permits diagnosis of chronic fatigue syndrome (CFS) by analyzing peripheral blood mononuclear cell subset populations and activation markers. A positive diagnosis for CFS is associated with an increase in the percentage of CD8+ cells showing CD38 or HLA-DR cell markers or a decrease in CD11b markers in CD8+ cells. The analysis is preferably performed using fluorochrome-labelled monoclonal antibodies specific for a determinant of the above subset cells and activation markers.
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