Dopamine receptor ligands and imaging agents
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United States of America Patent
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Jun 20, 1995
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May 24, 1994
filing date -
Apr 17, 1989
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Expired
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Abstract
Novel CNS dopamine D-2 receptors, such as the compound 5-iodo-7-N-[(1-ethyl-2-pyrrolidinyl)methyl]carboxamide-2,3-dihydrobenzofuran, are disclosed. These compounds are useful as imaging agents for D-2 receptors in the human brain and exhibit good brain retention and in vivo stability.
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