Transglutaminase cross-linkable polypeptides and methods relating thereto

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United States of America Patent

PATENT NO 5428014
SERIAL NO

08106509

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Abstract

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Polypeptides of from 3-120 amino acid residues comprising a segment of the formula Gln-Y-Lys, wherein Y is a spacer peptide of 1 to 12, wherein said polypeptides are cross-linkable by a transglutaminase, homo- and copolymers containing such polypeptides are disclosed. The homo- and co-polymers disclosed herein are useful in tissue sealant and wound healing formulations.

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Patent Owner(s)

Patent OwnerAddress
ZYMOGENETICS INC1201 EASTLAKE AVENUE EAST SEATTLE WA 98102

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Busby, Sharon J Seattle, WA 6 306
Labroo, Virender Mill Creek, WA 6 119

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