Polymer particles and method for preparing by polymerization of encapsulated monomers
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United States of America Patent
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Jul 11, 1995
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N/A
app pub date -
Nov 22, 1993
filing date -
Nov 22, 1993
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Abstract
A method for preparing polymer particles having diameters within the range from less than 0.1 micron to about 200 microns is described. The method involves encapsulating at least one water insoluble monomer within a water soluble polymer containing at least one thiol functional group. This is accomplished by combining an organic phase containing the monomers and a free radical source with an aqueous phase containing the polymer to form a two phase mixture, and subjecting the two phase mixture to agitation or ultrasonic irradiation. This invention allows for the preparation of polymer particles with sizes not available by conventional suspension or emulsion polymerization methods. It also provides for polymer particles within the specifed size range having compositions not readily obtained by other polymerization methods. The polymer particles made by this method have an exterior portion of water soluble polymer bound to an interior polymer. The exterior polymer, when it is a condensation polymer such as for example a protein, may be removed by acid hydrolysis.
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