Bispilocarpic acid ester derivatives and process for their preparation
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United States of America Patent
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Jul 25, 1995
Grant Date -
N/A
app pub date -
May 26, 1993
filing date -
Nov 30, 1990
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The object of the invention are bispilocarpates useful in the treatment of glaucoma and having the formula ##STR1## wherein A) Y is hydrogen or the acyl group ##STR2## and W is the group --O--A--O--Z--Y', wherein Y' is hydrogen or the acyl group ##STR3## the groups R and R' having different meanings and may be the same or different and A is an aliphatic, aromatic or heterocyclic bridging group, and --Z--Y' is ##STR4## or B) W is OR, wherein R has the same meaning as above, Y is ##STR5## where R' has the same meaning as above, B means the same as A and Z'--OR' is ##STR6## or C) W and Y together mean ##STR7## where the symbols have the same meanings as above.
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