Biological imaging emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
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United States of America Patent
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Aug 8, 1995
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app pub date -
Nov 24, 1993
filing date -
Nov 13, 1991
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Abstract
Oil and water emulsions containing alkylphosphoryl choline or alkylglycerophosphoryl choline surfactants are disclosed. The surfactants have the following general structures: ##STR1## In the above general structures, R.sub.1, R.sub.2 or R.sub.3 is alkyl, alkenyl, fluoroalkyl and alkenyl; and PC is the phosphoryl choline. The emulsions are useful as oxygen transport agents, artificial bloods or red blood cell substitutes. The emulsions are also useful as contrast agents for biological imaging by the modalities of nuclear magnetic resonance, x-ray and ultra sound.
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