Reduced and controlled surface binding of biologically active molecules
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United States of America Patent
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Aug 15, 1995
Issued Date -
N/A
app pub date -
Mar 11, 1993
filing date -
Jun 22, 1990
priority date (Note) -
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Abstract
Articles of manufacture which are adapted for use in contact with one or more biologically active agents are coated with a glassy carbohydrate film. The glassy film provides a reduced surface energy coating which exhibits a reduced degree of binding with biologically active agents. Methods for applying the glassy carbohydrate film are disclosed wherein the glassy film is adsorbed directly onto the article surface. The coated articles are for use both in vitro and in vivo where contact with biologically active agents is expected.
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