Method of delivering micellular particles encapsulating chemotherapeutic agents to tumors in a body
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United States of America Patent
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Aug 15, 1995
Grant Date -
N/A
app pub date -
Oct 22, 1984
filing date -
Mar 30, 1982
priority date (Note) -
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Abstract
A method is provided for delivering micellular particles containing chemotherapeutic agents and a marker to tumors within a body for the diagnosis and treatment of such tumors. The micellular particles are small, less than 2000 .ANG. and incorporate pure, neutral phospholipid molecules in their external surface. Enhanced delivery of the micellular particles containing marker and chemotherapeutic agents may be achieved by introducing an initial group of positively charged micellular particles to block the reticuloendothelial cells present in the body.
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