Methods of inhibiting thrombin
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United States of America Patent
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Aug 15, 1995
Grant Date -
N/A
app pub date -
Dec 21, 1993
filing date -
Dec 21, 1993
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method of inhibiting thrombin and its attending diseases and conditions comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidino, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
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