Organ specific emulsion
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United States of America Patent
Stats
-
Aug 29, 1995
Grant Date -
N/A
app pub date -
Dec 7, 1993
filing date -
Apr 23, 1991
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Disclosed are emulsions for intravenous administration based on lipophilic iodized and/or bromated substances with emulsifiers and containing derivatives of cyclopenta-phenanthrene, wherein the weight ratio between emulsifier and derivative in the emulsion is between 10:1 and 1:2. These emulsions are intended for use as X-ray contrast agent, particularly for visibilizing the presence of tumors, metastases and the like in liver and spleen. The derivative of cyclopenta-phenanthrene is preferably cholesterol, phytosterol, sitosterol, sigmasterol and/or campesterol. The invention also relates to a method for preparing the emulsion and to the use of the emulsion in the preparation of an X-ray contrast medium for computed tomographic examinations.
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