Array of oligonucleotides on a solid substrate
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United States of America Patent
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Aug 29, 1995
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N/A
app pub date -
Sep 30, 1992
filing date -
Jun 7, 1989
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Abstract
A method and apparatus for preparation of a substrate containing a plurality of sequences. Photoremovable groups are attached to a surface of a substrate. Selected regions of the substrate are exposed to light so as to activate the selected areas. A monomer, also containing a photoremovable group, is provided to the substrate to bind at the selected areas. The process is repeated using a variety of monomers such as amino acids until sequences of a desired length are obtained. Detection methods and apparatus are also disclosed.
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