Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends

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United States of America Patent

PATENT NO 5451409
SERIAL NO

08156223

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Abstract

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The present invention is directed to a novel sustained release matrix and oral dosage form comprising a homogeneous matrix formed from a wet granulation containing an effective amount of a medicament and a polymer blend of hydroxypropyl cellulose and hydroxyethyl cellulose. The present invention also discloses a novel process for making a sustained release oral dosage form comprising wet granulating a medicament with a polymer blend of hydroxypropyl cellulose and hydroxyethyl cellulose to form a homogeneous matrix, wherein the polymer blend is provided in an amount effective to control the release of said medicament, then forming the homogenous matrix into a solid oral dosage form.

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Patent Owner(s)

Patent OwnerAddress
MCNEIL-PPC INC601 OFFICE DRIVE FORT WASHINGTON PA 19034

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Babu, Suresh 6 Upper Field Rd., Morristown, NJ 07960 34 404
Day, Christopher H 237 Bridge St., Spring City, PA 19475 1 78
Musunuri, Shankar 7565 Charmant Dr., #508, San Diego, CA 92122 10 271
Rencher, William F 9455 Misty Grove Cove, Cardova, TN 38018 10 524
Schwing, James 304 Central Ave., Langhorne Manor, PA 19047 3 92

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