Method for minimizing and containing ischemic and reperfusion injury

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United States of America Patent

PATENT NO 5455229
SERIAL NO

07996347

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Abstract

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The present invention is a method for minimizing and containing injury caused when tissue is subject to ischemia and reperfusion. The method comprises administering certain derivatized tripeptide arginal compounds concurent with, or immediately after, reestablishing blood flow to the ischemic tissue. The method is particularly useful for minimizing and containing damage to the heart during evolving myocardial infarction.

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Patent Owner(s)

Patent OwnerAddress
ELI LILLY AND COMPANYLILLY CORPORATE CENTER INDIANAPOLIS IN 46285

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hahn, Richard A Carmel, IN 3 24
MacDonald, Brian R Fairland, IN 7 56
Shuman, Robert T Greenwood, IN 30 473
Smith, Gerald F Indianapolis, IN 36 559

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