Fluorescence detection of cell proliferation
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United States of America Patent
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Oct 10, 1995
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app pub date -
Apr 5, 1994
filing date -
Apr 5, 1994
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Abstract
The method of the present invention is directed at detecting non-invasively and in vivo the rate of proliferation of epithelial cells in a human patient. The method is based on determining the optical spectra, preferably the fluorescence excitation spectra, from affected and non-affected areas of epithelial cells, and then comparing the two spectra from these regions. In particular, applicants have discovered that when human or animal skin is irradiated with light centered near 295 nm, fluorescence having a distinct maximum near 360 nm is induced.
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