Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
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United States of America Patent
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Oct 10, 1995
Issued Date -
N/A
app pub date -
Feb 9, 1994
filing date -
Nov 27, 1990
priority date (Note) -
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Abstract
The present invention is concerned with a solid slow release oral pharmaceutical dosage unit which comprises a solid dosage unit made up of an admixture of a therapeutic dosage of an orally effective pharmaceutical product and a cross-linked polymer of amylose with a cross-linking agent selected from 2,3 dibromopropanol and epichlorohydrin, wherein the cross-linking of the polymer has been carried out with from about 0.1 to about 10 g of cross-linking agent per 100 g of amylose.
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