Method of manufacturing solid dispersion
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United States of America Patent
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Oct 10, 1995
Grant Date -
N/A
app pub date -
Nov 15, 1993
filing date -
Apr 16, 1991
priority date (Note) -
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Abstract
The object of this invention is to provide a process for producing a solid dispersion, which has overcome the disadvantages of the conventional production technology for solid dispersions. The invention comprises employing a twin-screw extruder in the production of a solid dispersion. In accordance with the invention, a solid dispersion can be expediently produced without heating a drug and a polymer to or beyond their melting points and without using an organic solvent for dissolving both components and the resulting solid dispersion has excellent performance characteristics.
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