Targeted transfection nanoparticles
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United States of America Patent
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Oct 24, 1995
Issued Date -
N/A
app pub date -
Nov 4, 1993
filing date -
Jun 22, 1990
priority date (Note) -
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Abstract
A biologically active composition for use in gene therapy and other transfection procedures. The composition is composed of nanocrystalline core particles which are coated with a layer that is designed to allow attachment of transfection agents (DNA/RNA segments or antisense fragments) without denaturing them. The composition may further include an exterior targeting membrane which provides selective targeting of the transfection agents to specific cell receptors.
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