Bioerodible polymers for solid controlled release pharmaceutical compositions
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United States of America Patent
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Oct 24, 1995
Issued Date -
N/A
app pub date -
Nov 15, 1993
filing date -
Apr 30, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Bioerodible ortho ester polymers useful for preparing solid form bioerodible pharmaceutical compositions such as pellets, capsules, suppositories and the like are provided. A novel synthetic method for preparing the polymers is provided as well as is a novel triol reactant. Synthesis involves a one-step reaction between a monomeric ortho ester and a triol. The pharmaceutical compositions of the invention are useful for the controlled release of therapeutic agents, and may be administered for a variety of purposes.
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