Methods for inhibiting vascular smooth muscle cell proliferation and restinosis

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United States of America Patent

PATENT NO 5462937
SERIAL NO

08422286

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods of inhibiting vascular smooth muscle cell proliferation and restinosis are disclosed comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR1## wherein R.sub.1 and R.sub.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sub.2 is ##STR3## and R.sub.4 is hydrogen or --OR.sub.1, and pharmaceutically acceptable salts and solvates thereof.

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Patent Owner(s)

  • ELI LILLY AND COMPANY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cullinan, George J Trafalgar, IN 77 1294
Singh, Jai P Carmel, IN 12 373
Wood, Dan L Indianapolis, IN 3 159

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