Method of preparing aryl(homo)piperazines
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United States of America Patent
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Oct 31, 1995
Grant Date -
N/A
app pub date -
Feb 12, 1993
filing date -
Feb 18, 1992
priority date (Note) -
Expired
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Abstract
The present invention is concerned with a method for the preparation of a compound of the general formula 2 ##STR1## by reaction of a compound of the formula 3 Ar--Y (3) with a compound of the general formula 4 ##STR2## wherein Ar means a (hetero)aryl group, preferably selected from phenyl, naphtyl, furyl, thienyl, pyridyl, bicylic heteroaryl and tricyclic heteroaryl, which (hetero)aryl group is optionally sustituted with one to five non-strongly-electron-withdrawing substituents; M is a metal from the groups I or II of the periodic table; R.sub.12 is an electronegative group; and is 0 or 1. The invention also relates to compounds prepared according to this method and to new substituted aryl(homo)piperazines.
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