Dihydropyridine-3,5-dicarboxylic acid ester derivatives

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United States of America Patent

PATENT NO 5463064
SERIAL NO

08238537

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Abstract

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A dextro-rotatory optical isomer of diastereoisomer A of (.+-.)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzylpyrrolidin-3-yl)ester 5-methyl ester is provided having the formula ##STR1## and wherein the melting point of the hydrochloride of the dextro-rotatory optical isomer is 223.degree. to 230.degree. C. (decomp.), or a pharmaceutically acceptable acid addition salt thereof.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ASTELLAS PHARMA INC.TOKYO290

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arima, Hideki Tokyo, JP 6 32
Isomura, Yasuo Tokyo, JP 29 321
Kojima, Tadao Saitama, JP 14 79
Murakami, Yukiyasu Saitama, JP 12 50
Okada, Minoru Tokyo, JP 113 1881
Takanobu, Kiyoshi Saitama, JP 3 6
Takenaka, Toichi Tokyo, JP 15 112
Tamazawa, Kazuharu Saitama, JP 4 6

Cited Art Landscape

Patent Info (Count) # Cites Year
 
YAMANOUCHI PHARMACEUTICAL CO., LTD. (1)
* 5364872 Dihydropyridine-3,5-dicarboxylic acid ester derivatives 4 1992
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
SAMSUNG FINE CHEMICALS CO., LTD. (1)
6566525 Preparation of N-substituted-hydroxycycloalkylamine derivatives 5 2001
 
COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (1)
8445700 Process for the preparation of optically active N-benzyl-3 hydroxypyrrolidines 0 2009
* Cited By Examiner