US Patent No: 5,464,388

Number of patents in Portfolio can not be more than 2000

Cardioplegia administration system and method

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ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

A cardioplegia administration system includes a tubing set, a positive displacement pump and a mixing system. The tubing set has a cardioplegia supply tube; a blood supply tube; and a cardioplegia administration tube connected to the cardioplegia and blood supply tubes. The positive displacement pump engages the cardioplegia administration tube to pump fluid therethrough. The mixing system includes pinch valves for alternately-continually pinching the cardioplegia and blood supply tubes to close and open the cardioplegia and blood supply tubes such that only one of the cardioplegia and blood supply tubes is open at a time, and a controller that controls the intervals during which the pinch valves are open to control the ratio of the cardioplegia medication and blood or blood substitute administered through the cardioplegia administration tube. The method of this invention includes the step, among others, of operating the pinch valves to close and open the cardioplegia and blood supply tubes so that only one of the cardioplegia and blood supply tubes is open at a time while controlling the intervals during which the pinch valves are open to control the ratio of the cardioplegia medication and blood or blood substitute administered through the cardioplegia administration tube.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
TERUMO CARDIOVASCULAR SYSTEMS CORPORATIONST PAUL, MN196

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Merte, Kenneth E Maple Grove, MN 11 417
O'Neill, William G Maple Grove, MN 29 943

Cited Art

Patent Info (Count) # Cites Year
 
BAXTER INTERNATIONAL INC. (4)
4,425,116 Control system for fluid flow apparatus 69 1982
4,526,515 Fluid pumping assembly including a prepackaged fluid circuit module 142 1982
4,637,813 Blood processing assembly including a prepackaged fluid circuit module 96 1982
5,207,642 Closed multi-fluid delivery system and method 210 1989
 
TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (4)
4,846,177 Combination fluid path and mount for heat exchanger 16 1988
5,057,278 Sterile loop calibration system 24 1990
5,094,820 Pump and calibration system 33 1990
5,403,281 Inline heat exchanger and cardioplegia system 131 1992
 
CHIRON VISION CORPORATION (3)
4,798,580 Disposable peristaltic pump cassette system 132 1987
5,125,891 Disposable vacuum/peristaltic pump cassette system 82 1988
5,195,960 Disposable vacuum/peristaltic pump cassette system 79 1991
 
Baxter Travenol Laboratories, Inc. (2)
4,425,113 Flow control mechanism for a plasmaspheresis assembly or the like 51 1982
4,925,444 Closed multi-fluid delivery system and method 199 1987
 
DEPARTMENT OF TREASURY INTERNATIONAL REVENUE SERVICE DISTRICT OF (2)
4,372,304 Flow control system and restrictor for use therein 13 1980
4,681,563 Flow control system 39 1985
 
GRASEBY MEDICAL LIMITED (2)
4,673,389 Sequence valve for piggyback IV administration 18 1984
4,714,463 Sequence valve for piggyback IV administration with tube reversal prevention 55 1985
 
HOSPIRA, INC. (2)
5,304,126 Infusion system having plural fluid flow lines 39 1990
5,306,242 Recirculation through plural pump cassettes for a solution compounding apparatus 37 1992
 
Stewart-Naumann Laboratories, Inc. (2)
4,187,057 Peristaltic infusion pump and disposable cassette for use therewith 189 1978
4,256,437 Peristaltic infusion pump and method 110 1978
 
ALARIS MEDICAL, INC. (1)
4,626,241 Apparatus and method for controlling the parenteral administration of fluids 21 1985
 
ALCON LABORATORIES, INC. (1)
5,094,260 Proportional valve and pressure control system 23 1990
 
ALCON RESEARCH, LTD. (1)
5,267,956 Surgical cassette 139 1992
 
ANGAR SCIENTIFIC COMPANY, INC., A NJ CORP. (1)
4,259,985 Three-way solenoid-operated pinch valve assembly 24 1978
 
CAREFUSION 303, INC. (1)
5,320,502 Infusion device with disposable elements 12 1991
 
CHASE MANHATTAN BANK, THE (1)
5,403,277 Irrigation system with tubing cassette 33 1993
 
COOPER COMPANIES, INC., THE (1)
4,713,051 Cassette for surgical irrigation and aspiration and sterile package therefor 113 1985
 
COVIDIEN AG (1)
5,181,842 Peristaltic infusion device 32 1991
 
EDWARDS LIFESCIENCES CORPORATION (1)
5,358,481 Apparatus and methods for controlling mixtures of blood and cardioplegia 30 1993
 
FLUID MANAGEMENT, INC. (1)
5,328,057 Paint dispenser apparatus 42 1993
 
GILBARCO INC. (1)
4,793,589 Piston valve with proportional solenoid controlled pilot valve 17 1987
 
HALMA HOLDINGS, INC. (1)
4,524,802 Pinch valve 47 1984
 
HEMASCIENCE LABORATORIES, INC. (1)
4,888,004 Method and apparatus for purging tubing network of blood processing system 9 1987
 
ITT MANUFACTURING ENTERPRISES, INC. (1)
5,350,083 Condiment dispensing device 16 1993
 
IVY MEICAL, INC. (1)
4,493,710 Intravenous drip rate control device 30 1983
 
Lever Brothers Company (1)
4,830,581 Apparatus for dispensing measured quantities of a liquid material 5 1987
 
MEDICAL TECHNOLOGY LTD., A LIMITED PARTNERSHIP (1)
4,537,561 Peristaltic infusion pump and disposable cassette for use therewith 175 1983
 
MEDTRONIC, INC. (1)
5,154,693 Flow control device having selectable alternative fluid pathways 32 1990
 
Oximetrix, Inc. (1)
4,842,584 Disposable fluid infusion pumping chamber cassette and drive mechanism thereof 79 1987
 
POLAROID CORPORATION (1)
4,445,826 Peristaltic pump apparatus 23 1982
 
QMI MEDICAL, INC. (1)
5,385,540 Cardioplegia delivery system 109 1993
 
SMITH METER INC. (1)
4,333,486 Electronic valve controller 10 1980
 
Staar Surgical Company, Inc. (1)
4,735,558 Peristaltic pump latching mechanism 64 1986
 
SULTAN CHEMISTS, INC. (1)
5,199,604 Irrigation system and method for delivering a selected one of multiple liquid solutions to a treatment site 65 1991
 
The Coca-Cola Company (1)
4,889,148 Flow control valve for a dispensing system 17 1988
 
WABCO Westinghouse Fahrzeugbremsen GmbH (1)
4,887,636 Apparatus for the continuous control of solenoid valves which are normally designed for intermittent operation 9 1986
 
WIEST, PETER P. (1)
4,998,914 Procedure for the perfusion of cavities in objects and device for executing the procedure 48 1989
 
Other [Check patent profile for assignment information] (9)
4,249,923 Cardioplegic fluid refrigeration and delivery system 46 1979
4,496,133 Pinch valve assembly 9 1982
4,512,764 Manifold for controlling administration of multiple intravenous solutions and medications 82 1982
4,559,036 Apparatus for controlling administration of multiple intravenous solutions and medications 125 1983
4,651,898 Milk dispenser 21 1984
4,874,359 Power infuser 81 1987
4,993,594 Multi-constituent mixing and metering dispenser 27 1989
5,044,902 Cartridge for peristaltic pump with a flexible tube, and peristaltic pump fitted with such a cartridge 26 1990
5,318,515 Intravenous flow regulator device and associated method 31 1992

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
BAXTER INTERNATIONAL INC. (7)
7,238,164 Systems, methods and apparatuses for pumping cassette-based therapies 37 2002
8,323,231 Method and apparatus for monitoring and controlling peritoneal dialysis therapy 0 2006
8,361,023 Dialysis system with efficient battery back-up 0 2007
7,998,115 Dialysis system having optical flowrate detection 2 2007
7,731,689 Dialysis system having inductive heating 0 2007
7,744,554 Cassette alignment and integrity testing for dialysis systems 7 2007
8,206,338 Pumping systems for cassette-based dialysis 0 2007
 
ABBOTT MEDICAL OPTICS INC. (1)
6,585,683 Tubing management manifold with tubing captures 1 2001
 
ACIST MEDICAL SYSTEMS, INC. (1)
8,262,610 Catheter fluid control system 0 2008
 
BIOANALYTICAL SYSTEMS, INC. (1)
6,871,660 Pinch valve and method of operating same 4 2002
 
FENTIS, ROBERT (1)
6,712,796 High hysteresis valve 24 2000
 
MEDTRONIC AVECORE CARDIOVASCULAR, INC. (1)
5,997,816 Heat exchanger for medical applications 19 1997
 
QMI MEDICAL, INC. (1)
5,588,816 Disposable cassette for cardioplegia delivery system 79 1995
 
Sloan Valve Company (1)
6,557,729 Soap dispensing system with single soap pump and two unpressurized soap containers 3 2001
 
TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (1)
5,755,686 Antegrade/retrograde switch for cardioplegia cannulae 8 1997
 
Other [Check patent profile for assignment information] (4)
6,419,662 Continuous irrigation Y-tubing control valve device and system 3 2001
8,353,864 Low cost disposable infusion pump 0 2009
8,197,235 Infusion pump with integrated permanent magnet 0 2009
8,292,839 Recirculation switch for blood cardioplegia 0 2009