Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
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United States of America Patent
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Nov 14, 1995
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N/A
app pub date -
Nov 25, 1992
filing date -
Nov 25, 1992
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Abstract
Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and n are as defined herein. The novel compounds are useful for modulating gene expression of retinoic acid receptors, vitamin D receptors and thyroid receptors. Pharmaceutical compositions and methods for modulating gene expression are provided as well.
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