Chemiluminescent acridinium salts

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United States of America Patent

PATENT NO 5468646
SERIAL NO

08368258

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Abstract

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Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a sulfonamide and acylating with an activated carboxylic acid of an acridine or isomer thereof. The N-sulfonyl-9-acridinium carboxamide and isomers may be conjugated to antigens, haptens, antibodies, and nucleic acids for use in chemiluminescent assays.

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Patent Owner(s)

  • ABBOTT LABORATORIES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, Larry G Grayslake, IL 5 222
Mattingly, Phillip G Grayslake, IL 42 858

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