Composition comprising a tramadol material and any of codeine, oxycodone or hydrocodone and their use
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United States of America Patent
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Nov 21, 1995
Issued Date -
N/A
app pub date -
Jun 30, 1994
filing date -
Sep 6, 1991
priority date (Note) -
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Abstract
This invention relates to compositions comprising a tramadol material selected from the group consisting of tramadol, its stereoisomers and its pharmaceutically acceptable salts and either codeine or oxycodone, and their use in treating pain. When the components, i.e., tramadol materials and either of codeine or oxycodone, of the composition are within certain ratios of pharmacological effects of the compositions are superaddditive (synergistic).
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