Family of anti-carcinoembryonic antigen chimeric antibodies

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United States of America Patent

PATENT NO 5472693
SERIAL NO

08017570

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention discloses novel chimeric monoclonal antibodies directed against human carcinoembryonic antigen, having antigen-specific variable regions. DNA constructs for the light and heavy chain variable regions comprising the novel antibodies of the invention are also disclosed. Eukaryotic host cells capable of expression of the chimeric antibodies and comprising the novel chimeric antibody-encoding DNA constructs are also described.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL INSTITUTES OF HEALTHNATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCE 9800 MEDICAL CENTER DRIVE ROCKVILLE MD 20850
DOW CHEMCIAL COMPANY THE2030 DOW CENTER ABBOTT ROAD MIDLAND MI 48640

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gourlie, Brian B Midland, MI 7 278
Kaplan, Donald A Cincinnati, OH 14 654
Mezes, Peter S Midland, MI 31 620
Rixon, Mark W Midland, MI 53 354
Schlom, Jeffrey Potomac, MD 101 1276

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