Family of anti-carcinoembryonic antigen chimeric antibodies

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United States of America Patent

PATENT NO 5472693
SERIAL NO

08017570

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention discloses novel chimeric monoclonal antibodies directed against human carcinoembryonic antigen, having antigen-specific variable regions. DNA constructs for the light and heavy chain variable regions comprising the novel antibodies of the invention are also disclosed. Eukaryotic host cells capable of expression of the chimeric antibodies and comprising the novel chimeric antibody-encoding DNA constructs are also described.

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Patent Owner(s)

  • THE DOW CHEMICAL COMPANY;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gourlie, Brian B Midland, MI 7 268
Kaplan, Donald A Cincinnati, OH 14 647
Mezes, Peter S Midland, MI 31 600
Rixon, Mark W Midland, MI 53 334
Schlom, Jeffrey Potomac, MD 99 1205

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