Benzothiophene derivative
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United States of America Patent
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Dec 5, 1995
Grant Date -
N/A
app pub date -
May 13, 1994
filing date -
Nov 15, 1991
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A benzothiophene derivative represented by the formula ##STR1## or a salt thereof has an excellent antiestrogenic activity, and is useful as a therapeutic agent of breast cancer, endometrial cancer, endometriosis, mastopathy, etc. This compound is characterized in that the 2-position (the substituent R.sup.2) of the benzothiophene nucleus is substituted by a halogen atom; a lower alkyl group; or a cycloalkyl or cycloalkenyl group optionally substituted by a lower alkyl group, a hydroxyl group, acyloxy group or an oxo group.
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