Method of making intraocular lenses with injectable collagen-based compositions

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United States of America Patent

PATENT NO 5476515
SERIAL NO

08158019

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Abstract

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Injectable collagen-based compositions can be used in methods to fill a lens capsular sac, following lens extraction procedures, to form a new intraocular lens. Purified soluble or partially fibrillar collagen may be modified with acylating agents, sulfonating agents or combinations thereof to form a clear, transparent collagen composition having indices of refraction between about 1.2 to 1.6. The modified collagen may injected into a lens capsular sac to form an intraocular lens (IOL) in situ. The IOL is clear, transparent, resistant to epithelialization and is capable of accommodation. The collagen-based IOL produced by the method of the present invention may remain in its original viscous liquid state or may be polymerized into a soft gel. The collagen-based IOL may be used to replace diseased or natural lens to treat cataracts, presbyopia, myopia and hyperopia.

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Patent Owner(s)

Patent OwnerAddress
COLLAGEN MATRIX TECHNOLOGIES INC660 GLADES ROAD STE 210 A FLORIDA CORPORATION BOCA RATON FL 33431

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DeVore, Dale P Chelmsford, MA 49 2299
Kelman, Charles D New York, NY 77 5615

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