Method for preventing tissue adhesion

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United States of America Patent

PATENT NO 5480436
SERIAL NO

08279811

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Abstract

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A device for preventing adhesions or binding of tissue to tissue or of tissue to bone which comprises a composite of a first layer and a second layer, each of which comprises a biodegradable polymer, such as, for example, a polyethylene glycol/polybutylene terephthalate copolymer. The first layer is selected from the group consisting of a non-porous layer and a porous layer having a pore size no greater than 3.mu.. The second layer has pores which have a pore size of from about 30.mu. to about 250.mu.. The device is placed between two tissues or between tissue and bone. Such a composite device provides for tissue growth into the second layer, while the first layer acts as an adhesion-preventing barrier, and enables attachment of the device to tissue without suturing. Alternatively, the device comprises the first layer hereinabove mentioned and a second layer which is an adherence layer and which adheres to tissue and/or bone.

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Patent Owner(s)

Patent OwnerAddress
CHIENNA B VPROF BRONKHORSTLAAN 10D 3723 MB BILTHOVEN NETHERLANDS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bakker, Dirkjan Alpen a/d Rijn, NL 7 301
Bakkum, Erica A Haarlem, NL 2 150
van, Blitterswlijk Clemens A Hekendorp, NL 1 82

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