Formulations for sustained release dressings and their use
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United States of America Patent
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Jan 2, 1996
Issued Date -
N/A
app pub date -
May 26, 1992
filing date -
Oct 23, 1989
priority date (Note) -
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Abstract
The invention concerns a sustained release formulation comprising an agent (A) which is to be released and a vehicle (B) therefor. The vehicle comprises a hydrophilic component such as a polyhydroxylated organic substance such as a polyethylene glycol, glycerol, sorbitol, mannitol or lactose and curable silicone composition which is capable of curing at ambient temperature and contains a polysiloxane having alkylhydrogen units, a polysiloxane having unsaturated groups and a platinum or rhodium catalyst. The formulation may be applied to the human or animal body or a cavity in the latter to cure in situ to give a dressing capable of sustained release of the therapeutic or diagnostic agent (A) to the body. The invention is applicable in the field of pharmacy.
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