Hemoproteins for inhibition of nitric oxide-mediated hypotension and septic shock
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United States of America Patent
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Jan 2, 1996
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N/A
app pub date -
Jan 18, 1994
filing date -
Feb 19, 1992
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Abstract
The invention is directed to a method for the prophylaxis or treatment of an animal for deleterious physiological effects such as systemic hypotension caused by nitric oxide production induced by a biological response modifier. Examples of such biological response modifiers include but are not limited to a cytokine and an endotoxin. The invention is also directed to a method for the treatment of septic shock. Hemoproteins such as hemoglobin, myoglobin, hemalbumin and methemalbumin, for example, are useful when administered to a hypotensive patient.
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