Peptides derived from the envelope glycoprotein of HIV viruses, their applications to the detection of infection caused by these viruses and to the vaccination against AIDS
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United States of America Patent
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Jan 2, 1996
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N/A
app pub date -
Sep 2, 1993
filing date -
Jan 16, 1990
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Abstract
Peptides are derived from the envelope glycoprotein of HIV virus and having one of the following formulae ##STR1## in which X represents an NH.sub.2 group which is free or converted into an amide by one or two alkyl groups comprising from 1 to 5 carbon atoms, and Z represents either an OH group which is free or present as an alkoxy and thereby containing an alkyl group comprising from 1 to 5 carbon atoms, and in which at least one of the Cys residues is deleted, substituted or protected. The peptides are applied to the detection of infection caused by the viruses HIV-1 and/or HIV-2 and to the vaccination against AIDS.
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