Complexes of nitric oxide with cardiovascular amines as dual acting cardiovascular agents
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United States of America Patent
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Jan 9, 1996
Grant Date -
N/A
app pub date -
Mar 17, 1994
filing date -
Mar 17, 1994
priority date (Note) -
Expired
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Abstract
Novel complexes of nitric oxide (NO) and amines are described where the amine is a known cardiovascular agent having at least one or more primary or secondary amino groups and whereby the resulting complex is capable under physiological conditions of releasing in vivo dual active ingredients, the NO and the known cardiovascular agent. The complexes are used for treating cardiovascular diseases and for the prophylactic or therapeutic treatment of restenosis.
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