Sustained-release drug delivery system
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United States of America Patent
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Jan 16, 1996
Grant Date -
N/A
app pub date -
Mar 28, 1994
filing date -
Mar 28, 1994
priority date (Note) -
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Abstract
A sustained-release pharmaceutical composition comprising a highly soluble pharmaceutical agent, such as selegiline, in a pharmaceutical carrier comprising a hydrophilic polymer dispersed in a hydrophobic matrix. A hydrophilic microenvironment is created in a hydrophobic matrix by incorporating hydrophilic polymers within a hydrophobic matrix. Optionally, a binder, preferably a polyhydroxylated compound, ca also be added.
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