Radiofrequency plasma biocompatibility treatment of inside surfaces
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United States of America Patent
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Jan 23, 1996
Issued Date -
N/A
app pub date -
Oct 27, 1993
filing date -
Nov 8, 1990
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Abstract
Internal polymeric surfaces of medical devices are provided that have enhanced biocompatibility properties. The internal polymeric surface presents an anti-thrombogenic, fibrinolytic or thrombolytic interface with body fluids such as blood flowing through medical device tubing during implantation for medical procedures. The biocompatibility enhancing agent is secured to the polymeric substrate by a spacer molecule which is covalently bound to the internal polymeric surface which had been subjected to radiofrequency plasma treatment with a low pressure plasma medium of water vapor, oxygen or combination of water vapor and oxygen gas.
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