Density gradient medium for the separation of cells
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United States of America Patent
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Feb 6, 1996
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app pub date -
Jan 31, 1994
filing date -
Jan 31, 1994
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Abstract
A density gradient medium for the isolation and enrichment of rare cells, including fetal nucleated erythrocytes from a peripheral blood sample is described. The medium comprises a colloidal density gradient medium dispersed in a meltable gel. In one aspect of the invention, the density gradient medium is hypertonic to facilitate separation of maternal red blood cells from fetal blood cells.
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