Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
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United States of America Patent
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Feb 6, 1996
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app pub date -
Mar 24, 1993
filing date -
May 13, 1992
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Abstract
Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to inhibit telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity.
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