Targeted thermal release of drug-polymer conjugates
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United States of America Patent
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Feb 13, 1996
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N/A
app pub date -
Sep 26, 1994
filing date -
Sep 26, 1994
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Abstract
Thermal drug treatment of tumor tissue is obtained by attaching a thermally active drug to carrier molecules which have an affinity to tumor tissue. Localized heating is performed on the tumor tissue, thereby activating the drug in the tumor tissue. The end result may be concentrated delivery of a drug to a chosen tissue, or, in the case where the drug creates a toxin when heated, selective tissue destruction of a selected locations heated. The localized heat may be applied by focused ultrasound heating.
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