US Patent No: 5,490,962

Number of patents in Portfolio can not be more than 2000

Preparation of medical devices by solid free-form fabrication methods

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Abstract

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Solid free-form techniques for making medical devices for controlled release of bioactive agent and implantation and growth of Cells are described using computer aided design. Examples of SFF methods include stereo-lithography (SLA), selective laser sintering (SLS), ballistic particle manufacturing (BPM), fusion deposition modeling (FDM), and three dimensional printing (3DP). The macrostructure and porosity of the device can be manipulated by controlling printing parameters. Most importantly, these features can be designed and tailored using computer assisted design (CAD) for individual patients to optimize therapy.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
MASSACHUSETTS INSTITUTE OF TECHNOLOGYCAMBRIDGE, MA4436

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cima, Linda G Lexington, MA 11 931
Cima, Michael J Winchester, MA 165 3570

Cited Art Landscape

Patent Info (Count) # Cites Year
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (2)
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5,204,055 Three-dimensional printing techniques 378 1989
 
MESOBLAST INTERNATIONAL SÀRL (2)
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TEXAS INSTRUMENTS INCORPORATED (1)
5,260,009 System, method, and process for making three-dimensional objects 109 1992
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
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Other [Check patent profile for assignment information] (2)
4,609,551 Process of and material for stimulating growth of cartilage and bony tissue at anatomical sites 193 1984
4,620,327 Process of adapting soluble bone protein for use in stimulating osteoinduction 83 1984

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
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SHIONOGI INC. (13)
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6,669,683 Thermally-activated microchip chemical delivery devices 114 2003
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7,497,846 Hermetically sealed microchip reservoir devices 3 2004
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CARDIAC PACEMAKERS, INC. (8)
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MICRON TECHNOLOGY, INC. (7)
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THE INVENTION SCIENCE FUND I, LLC (7)
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THE UNIVERSITY OF LIVERPOOL (7)
7,537,664 Laser-produced porous surface 5 2003
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GEORGIA TECH RESEARCH CORPORATION (6)
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THEKEN SPINE, LLC (5)
6,213,168 Apparatus and method for dispensing of powders 9 1999
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6,341,952 Fabrication of tissue products with additives by casting or molding using a mold formed by solid free-form methods 13 2001
6,772,026 System and method for rapidly customizing design, manufacture and/or selection of biomedical devices 146 2001
7,122,057 Method and apparatus for engineered regenerative biostructures such as hydroxyapatite substrates for bone healing applications 26 2002
 
REMON MEDICAL TECHNOLOGIES LTD. (4)
7,621,905 Devices for intrabody delivery of molecules and systems and methods utilizing same 16 2003
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THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (4)
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KENSEY NASH CORPORATION (3)
7,963,997 Device for regeneration of articular cartilage and other tissue 4 2004
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PENTRON CLINICAL TECHNOLOGIES, LLC (3)
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3M INNOVATIVE PROPERTIES COMPANY (2)
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SMED-TA/TD, LLC (2)
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ADVANCIS PHARMACEUTICAL CORPORATION (1)
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GSLE SUBCO L.L.C. (1)
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RENEURON, INC. (1)
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RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (1)
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SPX CORPORATION (1)
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THE CURATORS OF THE UNIVERSITY OF MISSOURI (1)
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THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
7,509,240 Solid freeform fabrication of structurally engineered multifunctional devices 3 2002
 
TREDEGER CORPORATION (1)
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UNITED STATES GYPSUM COMPANY (1)
8,323,429 Method for preparing three-dimensional plaster objects 0 2009
 
UNITED TECHNOLOGIES CORPORATION (1)
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WAKE FOREST UNIVERSITY HEALTH SCIENCES (1)
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Other [Check patent profile for assignment information] (3)
5,590,454 Method and apparatus for producing parts by layered subtractive machine tool techniques 12 1994
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6,593,008 Modified freeform fabricated part and a method for modifying the properties of a freeform fabricated part 3 2002