Compositions of N-(phosphonoacetyl)-L-aspartic acid and methods of their use as broad spectrum antivirals

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United States of America Patent

PATENT NO 5491135
SERIAL NO

08032234

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Abstract

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Compositions and methods are disclosed which utilize the broad spectrum antiviral activity of PALA. This compound and its pharmaceutically acceptable analogs possess potent activity while displaying minimal toxicity and, therefore, are characterized by a relatively high therapeutic index. Compositions optionally containing other therapeutic agents, such as other antiviral agents, are also disclosed and are found to possess synergistic and/or additive antiviral activity.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE ONCOLOGY INCGAITHERSBURG MD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blough, Herbert A Berwyn, PA 3 42

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