Method of preparing optically active cyanohydrin derivatives

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United States of America Patent

PATENT NO 5493047
SERIAL NO

08161420

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Abstract

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The invention relates to a method of preparing an optically active cyanohydrin carboxylic acid ester from an optically active cyanohydrin of opposite configuration, wherein said starting cyanohydrin is converted with a carboxylic acid in the presence of a dialkyl azodicarboxylate and a triarylphosphine. The invention also relates to a method of preparing an optically active cyanohydrin of opposite configuration by a subsequent solvolysis of the ester obtained under conservation of the configuration.

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Patent Owner(s)

Patent OwnerAddress
DUPHAR INTERNATIONAL RESEARCH B VWEESP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brussee, Johannes Weesp, NL 12 53
Kruse, Chris G Weesp, NL 6 45
Van, Der Gen Arne Weesp, NL 5 38
Warmerdam, Erwin G J C Weesp, NL 1 1

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