Solutions for the perfusion, preservation and reperfusion of organs
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United States of America Patent
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Mar 12, 1996
Issued Date -
N/A
app pub date -
Aug 18, 1994
filing date -
Nov 20, 1990
priority date (Note) -
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Abstract
Perfusion and preservation and/or reperfusion solutions for surgery and organ transplantation, including that of the heart, a feature of which solutions is the inclusion of at least one antioxidant compound, such as a trapping agent for free oxygen radicals, in particular glutathione in the reduced state or N-acetylcysteine, said solutions possessing a zero or greatly reduced partial pressure of oxygen which is maintained substantially at this value up to the time of use. The solution is preferably presented in flexible bags impermeable to oxygen.
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